Silvia Lemma Ph.D. (Università degli Studi di Bologna); Pharmaceutical Biotechnology (Università degli Studi di Bologna)
Research Fellow - Assegnista di ricerca, University of Bologna, Bologna, Emilia-Romagna · Italy
Editorial leadership for International Journal of Bone and Mineral Metabolism
Research interests
- Basal Metabolism Of The Cells Of The Bone Microenvironment: Osteoclast
- Osteoblast
- Osteocyte
- And Mesenchymal Stem Cell. Adaptation Of Bone Metabolism In Pathological Conditions
- Such As Ketoacidosis. Ketone Bodies Metabolism In Osteolysis. Metabolism Of Osteolytic Bone Metastasis
- And Strategies To Prevent Osteolytic Lesion Formation. Metabolism Of Benign Bone Tumors
- Including Giant Cell Tumor Of Bone. Microenvironment Of Osteolytic Diseases. The Acidic Microenvvironment In Tumor Formation
- Progression. Tumour Microenvironment
- Metabolism As A Target For Novel Therapies For Patients With Bone Tumors. Housekeeping Gene Validation In Cancer Stem Cells
- Microenvironment Adaptations. Tumour Microenvironment
- Metabolism As A Target For Novel Therapies For Patients With Bone Tumors. Mechanism Of Drug Resistance Of Aggressive Tumors. Cancer-Induced Bone Pain. Housekeeping Gene Validation In Cancer Stem Cells
- Microenvironment Adaptations. Chromatin Compaction
- Post-Translation Modifications Of Histones In Tumorigenesis. Mechanism Underling The Metastatic Process In Aggressive Tumors
Biography
Dr. Silvia Lemma is a Research Fellow (Assegnista di ricerca) at the University of Bologna, Italy, where she also completed her PhD at the Università degli Studi di Bologna. Her research focuses on cancer metabolism, tumor microenvironment acidosis, and bone metastases, with particular emphasis on the metabolic interplay between cancer cells and stromal components in osteolytic processes. She has made significant contributions to understanding energy metabolism in osteoclasts, drug resistance mechanisms in osteosarcoma, and the role of intratumoral acidosis in cancer-induced bone pain. Her most-cited work, "Validation of Suitable Housekeeping Genes for the Normalization of mRNA Expression for Studying Tumor Acidosis" (2018), has been cited 20 times and reflects her expertise in molecular methodologies for cancer research.
Selected publications
- Validation of Suitable Housekeeping Genes for the Normalization of mRNA Expression for Studying Tumor Acidosis 2018 cited 20×
- Benign albeit glycolytic: MCT4 expression and lactate release in giant cell tumour of bone 2020 cited 2×
Ranked by citation impact (Crossref) where available, newest otherwise · verified via ORCID.
Considering IJBM for your work?
This journal is guided by Silvia Lemma (Research Fellow - Assegnista di ricerca, University of Bologna, Bologna, Emilia-Romagna) and a peer-review board of practising researchers. Open access, author-retained copyright (CC BY), and a clear editorial process.