Dr. G. Hossein Ashrafi PhD
Kingston University London ORCID: 0000-0002-4516-5111 · United Kingdom
Editorial leadership for Journal of Biotechnology and Biomedical Science ISSN 2576-6694
Research interests
- Human Papillomavirus (Hpv) Oncogenesis Breast Cancer Etiology
- Pathology Viral Immune Evasion (Hpv E5 Protein) Molecular
- Cell Biology Of Cancer Transcriptomics
- Gene Expression Analysis Cervical
- Anogenital Cancer Diagnostics
- Global Cancer Prevention
Biography
Dr. G. Hossein Ashrafi is a highly experienced researcher and lecturer specializing in Pathology, Cancer Biology, and Molecular Virology. His principal research area is the study of Human Papillomavirus (HPV) oncogenesis, with a specific focus on the virus’s molecular mechanisms in non-cervical malignancies, particularly Breast Cancer and anogenital tumors. Dr. Ashrafi's work explores how HPV oncoproteins, such as E5, E6, and E7, modulate host cell pathways and facilitate immune evasion. His current research utilizes transcriptomic analysis and molecular techniques to elucidate the controversial association between high-risk HPV and cancer development.
Education Details
- Ph.D: Beatson Institute for Cancer Research, University of Glasgow
- FIBMS (Fellow of the Institute of Biomedical Science)
- FHEA (Fellow of the Higher Education Academy)
Professional Background
- Faculty Member (Current), School of Life Sciences, Pharmacy and Chemistry, Kingston University London, UK.
- Expertise (Current): Pathology and Cancer Biology.
- Previous/Concurrent Researcher at institutions including the University of Glasgow, UK.
Achievements
- Internationally recognized expert in the molecular pathology of Human Papillomavirus (HPV) infections and cancer etiology.
- Key publications focusing on the viral oncoprotein E5 and its role in downregulating host immune responses (e.g., HLA Class I).
- Extensive research collaboration network addressing the prevalence of HPV in diverse cancer types (breast, prostate, oesophageal, bladder).
Current Research Projects
Dr. Ashrafi's current research utilizes molecular and genetic techniques to explore viral and host interactions:
- Transcriptomic analysis of HPV-positive tissues (e.g., oesophageal) to identify gene expression changes that precede malignancy.
- Investigating the correlation and mechanisms through which HPV contributes to the etiology of breast and prostate cancer.
- Assessing the regulatory effects of natural products (e.g., Ficus carica latex) on cell cycle progression in HPV-positive cancer cell lines.
Academic Profiles of Dr. G. Hossein Ashrafi
Explore his academic and professional presence across trusted platforms.
Selected publications
- Exosomes in HPV-Associated Cancers: From Biomarkers to Engineered Therapeutics Recent 2025 cited 5×
- Ficus carica Latex Modulates Immunity-Linked Gene Expression in Human Papillomavirus Positive Cervical Cancer Cell Lines: Evidence from RNA Seq Transcriptome Analysis 2023 cited 4×
- Molecular Insights into HPV-Driven Head and Neck Cancers: From Viral Oncoproteins to Precision Therapeutics Recent 2025 cited 3×
- Transcriptomic Analysis of HPV-Positive Oesophageal Tissue Reveals Upregulation of Genes Linked to Cell Cycle and DNA Replication 2024 cited 3×
- Papillomavirus-Induced Oncogenesis: Bridging Molecular Mechanisms, Diagnostics, and Global Prevention Strategies Recent 2025 cited 2×
- Genome Editing Against HPV-Driven Cancers: From Bench to Clinic Recent 2025 cited 2×
Ranked by citation impact (Crossref) where available, newest otherwise · verified via ORCID.
Considering JBBS for your work?
This journal is guided by Dr. G. Hossein Ashrafi (Kingston University London ORCID: 0000-0002-4516-5111) and a peer-review board of practising researchers. Open access, author-retained copyright (CC BY), and a clear editorial process.