Editorial Board
Tauheed Ishrat
Department of Pharmacy, University of Georgia · united states
Editorial leadership for Journal of Advanced Pharmaceutical Science And Technology ISSN 2328-0182
Research interests
- My Research Interests Focus On The Molecular Events Underlying Neurological Diseases. In My Studies I Concentrate On Three Diseases: Parkinson
- Alzheimer
- Cerebral Stroke. The Long-Term Goal To Identify Potential New Drug Targets For The Development Of Causative Treatments. These Are Progressive Diseases Of The Nervous System Involving Damage Or Loss Of Neurons In The Brain. The Causes Of The Diseases Are Unknown But Recent Evidence Suggests A Multifactorial Origin Involving Genetic
- Environmental Factors. Considerable Efforts Have Been Made To Determine The Cellular Mechanisms That Might Underlie The Cell Death In These Diseases. Over The Years
- Several Pathogenic Hypotheses Have Been Proposed
- Including Oxidative Stress
- Apoptosis
- Excitotoxicity
- Inflammation
- Mitochondrial Dysfunction. However
- Up To Now It Is Not Known Which Of These Metabolic Pathways Participate In The Process Of Cell Death
- If
- How They Interact
- Which Genes Are Regulating This Complex Network
Biography
- Dr. Ishrat working as a Research scientist at University of Georgia, Augusta, GA.
- My research revolves around the importance of vascular protection in the acute stroke period to improve outcome of ischemic stroke.
- Also, I am trying to identify tactics for decreasing vascular damage after ischemic stroke in an attempt to develop new therapies for stroke patients.
Selected publications
- Thioredoxin-Interacting Protein (TXNIP) in Cerebrovascular and Neurodegenerative Diseases: Regulation and Implication 2018 cited 145×
- Tissue Plasminogen Activator Promotes TXNIP-NLRP3 Inflammasome Activation after Hyperglycemic Stroke in Mice 2020 cited 41×
- The Brain AT2R—a Potential Target for Therapy in Alzheimer’s Disease and Vascular Cognitive Impairment: a Comprehensive Review of Clinical and Experimental Therapeutics 2020 cited 30×
- Verapamil Prevents Development of Cognitive Impairment in an Aged Mouse Model of Sporadic Alzheimer’s Disease 2021 cited 22×
- Verapamil inhibits TXNIP-NLRP3 inflammasome activation and preserves functional recovery after intracerebral hemorrhage in mice 2022 cited 21×
- Verapamil as an Adjunct Therapy to Reduce tPA Toxicity in Hyperglycemic Stroke: Implication of TXNIP/NLRP3 Inflammasome 2021 cited 21×
Ranked by citation impact (Crossref) where available, newest otherwise · verified via ORCID.
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This journal is guided by Tauheed Ishrat (Department of Pharmacy, University of Georgia) and a peer-review board of practising researchers. Open access, author-retained copyright (CC BY), and a clear editorial process.